Little Effect Of Soy Isoflavones On Bone Loss In Postmenopausal Women: ISU Multi-Center Study
A previous six-month study by Iowa State University researchers had indicated that consuming modest amounts of soy protein, rich in isoflavones, lessened lumbar spine bone loss in midlife, perimenopausal women. But now an expanded three-year study by some of those same researchers does not show a bone-sparing effect in postmenopausal women who ingested soy isoflavone tablets, except for a modest effect at the femoral (hip) neck among those who took the highest dosage. The multi-center clinical trial of 224 postmenopausal women -- led by D. Lee Alekel, professor of nutrition and interim associate director of the Nutrition and Wellness Research Center (NWRC) at Iowa State, and supported by the National Institute of Arthritis, Musculoskeletal and Skin Diseases, one of the research institutes of the National Institutes of Health (NIH) -- was the longest ever conducted on the effects of soy isoflavones on bone mineral density (BMD).
BioMimetic Therapeutics Completes Submission Of PMA Application For FDA Approval Of Augment trade; Bone Graft
BioMimetic Therapeutics, Inc. (NASDAQ: BMTI) today announced it has submitted the third and final module of its Premarket Approval (PMA) application for marketing of Augment™ Bone Graft in the U.S. This final module, containing a comprehensive review of the clinical data related to Augment, completes the PMA application to the FDA. The Company previously announced the filing of both the pre-clinical pharmacology/toxicology and quality/manufacturing modules with the FDA in June of 2009. Upon receipt of the clinical module, the FDA begins its 45 day filing process as the first step in the formal review of the PMA. The Company expects the agency to schedule an advisory panel review sometime later in the year.
Don't Miss The Opportunity To Attend The Most Exciting Bone Meeting In The Asia-Pacific Region In 2010
Singapore meeting to feature top speakers, Meet-the-Expert Sessions, orthopaedic and diagnostic roundtables The International Osteoporosis Foundation (IOF) invites you to attend the IOF Regionals: 1st Asia-Pacific Osteoporosis Meeting to be held in Singapore from December 10 - 13, 2010. Visit http://www.iofbonehealth.org/singapore-2010 for complete information. Online registration and abstract submission opens April 15, 2010. Meeting Highlights Osteoporosis experts from the Asia-Pacific region and around the globe, will ensure an enriching scientific programme, to include: 12 plenary lectures by some of the key scientific opinion leaders in the bone arena 5 clinically-oriented Meet-the-Expert sessions Roundtable Symposia on orthopaedics and diagnostic techniques Poster sessions and oral presentations 6 Satellite Symposia and an informative exhibition Opportunity to submit your scientific abstract to the field's leading journal, Osteoporosis International, with top abstracts selected for oral presentation during the meeting.
New Material Mimics Bone To Create Better Biomedical Implants
A "metal foam" that has a similar elasticity to bone could mean a new generation of biomedical implants that would avoid bone rejection that often results from more rigid implant materials, such as titanium. Researchers at North Carolina State University have developed the metal foam, which is even lighter than solid aluminum and can be made of 100 percent steel or a combination of steel and aluminum. In a new paper, researchers have reported recent findings that, in addition to the extraordinary high-energy absorption capability and light weight of their novel composite foams, the "modulus of elasticity" of the foam is very similar to that of bone. Modulus of elasticity measures a material's ability to deform when pressure is applied and then return to its original shape when pressure is removed.
Kensey Nash Announces CE Mark Approval For Cartilage Repair Device
Kensey Nash Corporation (Nasdaq: KNSY), a leading medical technology company that provides innovative resorbable biomaterial solutions for a wide range of medical procedures, announced that it has received the CE Mark for the Company's Cartilage Repair Device. This approval allows for the marketing and sale of the Device, which incorporates a unique biomaterials technology for treating articular cartilage defects of the knee. The Kensey Nash Cartilage Repair Device (CRD) is a biphasic, bioresorbable scaffold intended to be implanted at the site of a focal articular cartilage lesion or osteochondral defect in the knee. The CRD is intended to serve as a scaffold for cellular and matrix in-growth in osteochondral defect repair such as bone and/or cartilage, which is not intrinsic to the stability of the tissue.
Mizzou Scientist Creates A Chicken Substitute, Providing A Low-Cost, Tasty Way To Add Soy To The Diet
Sure, some delicacies might taste just like chicken, but they usually feel and look much different. Soy meat alternatives, such as the soy burger, have become more popular recently, with increased sales of eight percent from 2007 to 2008. Now, scientists at the University of Missouri have created a soy substitute for chicken that is much like the real thing. The new soy chicken also has health benefits, including lowering cholesterol and maintaining healthy bones. Fu-Hung Hsieh, an MU professor of biological engineering and food science in the College of Agriculture, Food and Natural Resources and the College of Engineering, is leading the project to create a low-cost soy substitute for chicken.
Walking Linked To Eased Osteoarthritis
"Progressive walking" combined with glucosamine sulphate supplementation has been shown to improve the symptoms of osteoarthritis. Researchers writing in BioMed Central's open-access journal Arthritis Research and Therapy found that patients who walked at least two bouts of 1500 steps each on three days of the week reported significantly less arthritis pain, and significantly improved physical function. Dr Kristiann Heesch worked with a team of researchers from The University of Queensland, Australia, to carry out the trial in 36 osteoarthritis patients (aged 42 - 73 years). All patients received the dietary supplement for six weeks, after which they continued to take the supplement during a 12-week progressive walking program.
New Clinical Practice Guidelines For Treating Distal Radius Fractures Issued By AAOS
The American Academy of Orthopaedic Surgeons (AAOS) recently approved and released an evidence-based clinical practice guideline on the Treatment of Distal Radius Fractures. A distal radius fracture - one of the most common fractures in the body - usually occurs as a result of a fall. For example, a fall may cause someone to land on his or her outstretched hands, breaking the larger of the two bones in the forearm, near the wrist. In 2007, more than 261, 000 people visited the emergency room due to a distal radius fracture. "The Academy created this clinical practice guideline to improve patient care for those sustaining a distal radius fracture, " stated David Lichtman, MD, chair of this guideline workgroup.
Cartilage Replacement Using The Body's Own Cells: Fast, Affordable And A Perfect Fit
Injuries to joints and cartilage can have serious consequences, including osteoarthritis. Cartilage degeneration in joints is a widespread disease in Germany and worldwide. Prof. Dr. Prasad Shastri is an expert in tissue engineering (TE), tissue construction and tissue cultivation using the body's own cells. He is Professor of Biofunctional Macromolecular Chemistry at the Centre for Biological Signalling Studies (BIOSS), a Cluster of Excellence at the University of Freiburg, where he has been researching for the last year. Together with peers from Maastricht and Nashville, he has developed a fast and cost-efficient method for producing sufficient amounts of bone and cartilage tissue using the body's own cells.
Safer Hip, Knee And Dental Implants With Smart Coating
Researchers at North Carolina State University have developed a "smart coating" that helps surgical implants bond more closely with bone and ward off infection. When patients have hip, knee or dental replacement surgery, they run the risk of having their bodies reject the implant. But the smart coating developed at NC State mitigates that risk by fostering bone growth into the implant. The coating creates a crystalline layer next to the implant, and a mostly amorphous outer layer that touches the surrounding bone. The amorphous layer dissolves over time, releasing calcium and phosphate, which encourages bone growth. "The bone grows into the coating as the amorphous layer dissolves, resulting in improved bonding, or osseointegration, " says Dr.